Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF121Ring finger protein 121. (328 aa)    
Predicted Functional Partners:
CFAP161
Cilia and flagella associated protein 161.
      
 0.753
MOSPD2
Motile sperm domain containing 2.
      
 0.718
DIS3L2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
   
  
 0.665
TMTC3
Transmembrane O-mannosyltransferase targeting cadherins 3.
      
 0.657
MORN1
MORN repeat containing 1.
      
 0.620
MARCHF6
Membrane associated ring-CH-type finger 6.
      
 0.616
NOL3
CARD domain-containing protein.
      
 0.600
NUDC
Nuclear distribution C, dynein complex regulator.
      
 0.599
RNF185
RING-type domain-containing protein.
 
    
 0.568
LOC102455013
RING-type domain-containing protein.
 
    
 0.567
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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