STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP10Caspase 10; Belongs to the peptidase C14A family. (546 aa)    
Predicted Functional Partners:
FADD
Fas associated via death domain.
   
 0.988
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
   
0.983
TRADD
TNFRSF1A associated via death domain.
    
 0.974
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 0.968
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.919
FAS
Fas cell surface death receptor.
   
 0.885
K7FWT7_PELSI
Protein kinase domain-containing protein.
   
 0.870
K7FH17_PELSI
Uncharacterized protein; Belongs to the peptidase C14A family.
  
  
 
0.803
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.797
LOC102458875
Uncharacterized protein.
    
 0.774
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.