STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMMRHyaluronan mediated motility receptor. (689 aa)    
Predicted Functional Partners:
APLP2
Amyloid beta precursor like protein 2.
    
 0.614
APLP1
Amyloid beta precursor like protein 1.
    
 0.567
MRE11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
  0.508
RAD50
Zinc-hook domain-containing protein.
   
 0.473
MAPK10
Mitogen-activated protein kinase.
    
 0.471
MAPK8
Mitogen-activated protein kinase.
    
 0.471
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
  0.457
K7FSL9_PELSI
Link domain-containing protein.
     
 0.455
ATM
Non-specific serine/threonine protein kinase.
    
 0.449
MAPK9
Mitogen-activated protein kinase.
    
 0.446
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.