Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (661 aa)    
Predicted Functional Partners:
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
 
 0.951
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
   
 
 0.907
SHC3
SHC adaptor protein 3.
    
 0.877
SHC1
SHC adaptor protein 1.
    
 0.877
EGF
Epidermal growth factor.
     
 0.873
MATK
Tyrosine-protein kinase.
   
 0.854
CSK
Tyrosine-protein kinase.
   
 0.854
PDGFRB
Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.722
ERBB3
Recep_L_domain domain-containing protein.
    
 0.712
EGFR
Receptor protein-tyrosine kinase.
    
 0.712
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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