node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC102449041 | MED1 | ENSPSIP00000004054 | ENSPSIP00000007670 | Uncharacterized protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.742 |
LOC102449041 | NCOA1 | ENSPSIP00000004054 | ENSPSIP00000008403 | Uncharacterized protein. | Nuclear receptor coactivator. | 0.769 |
LOC102449041 | NCOA3 | ENSPSIP00000004054 | ENSPSIP00000013227 | Uncharacterized protein. | Nuclear receptor coactivator. | 0.769 |
LOC102449041 | RXRA | ENSPSIP00000004054 | ENSPSIP00000013390 | Uncharacterized protein. | Retinoid X receptor alpha. | 0.826 |
LOC102449041 | RXRG | ENSPSIP00000004054 | ENSPSIP00000005268 | Uncharacterized protein. | Retinoid X receptor gamma. | 0.826 |
MED1 | LOC102449041 | ENSPSIP00000007670 | ENSPSIP00000004054 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Uncharacterized protein. | 0.742 |
MED1 | NCOA1 | ENSPSIP00000007670 | ENSPSIP00000008403 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.598 |
MED1 | NCOA3 | ENSPSIP00000007670 | ENSPSIP00000013227 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.598 |
MED1 | NR1H3 | ENSPSIP00000007670 | ENSPSIP00000011575 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 3. | 0.755 |
MED1 | NR1H4 | ENSPSIP00000007670 | ENSPSIP00000006293 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 4. | 0.811 |
MED1 | PPARA | ENSPSIP00000007670 | ENSPSIP00000020600 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator activated receptor alpha. | 0.882 |
MED1 | PPARD | ENSPSIP00000007670 | ENSPSIP00000006387 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator activated receptor delta. | 0.637 |
MED1 | PPARG | ENSPSIP00000007670 | ENSPSIP00000012413 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.972 |
MED1 | RXRA | ENSPSIP00000007670 | ENSPSIP00000013390 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.800 |
MED1 | RXRG | ENSPSIP00000007670 | ENSPSIP00000005268 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor gamma. | 0.800 |
NCOA1 | LOC102449041 | ENSPSIP00000008403 | ENSPSIP00000004054 | Nuclear receptor coactivator. | Uncharacterized protein. | 0.769 |
NCOA1 | MED1 | ENSPSIP00000008403 | ENSPSIP00000007670 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.598 |
NCOA1 | NR1H3 | ENSPSIP00000008403 | ENSPSIP00000011575 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 3. | 0.844 |
NCOA1 | NR1H4 | ENSPSIP00000008403 | ENSPSIP00000006293 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 4. | 0.788 |
NCOA1 | PPARA | ENSPSIP00000008403 | ENSPSIP00000020600 | Nuclear receptor coactivator. | Peroxisome proliferator activated receptor alpha. | 0.733 |