STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCF7L2Transcription factor 7-like 2 (T-cell specific, HMG-box) (602 aa)    
Predicted Functional Partners:
CTNNB1
Catenin (cadherin-associated protein), beta 1, 88kDa
    
 0.984
NLK
Mitogen-activated protein kinase; Nemo-like kinase
   
 0.972
EP300
E1A binding protein p300
   
 0.967
CREBBP
CREB binding protein
   
 0.967
SMAD4
Mothers against decapentaplegic homolog; SMAD family member 4
    
 0.931
LEF1
Lymphoid enhancer-binding factor 1
    
0.867
SOX17
Uncharacterized protein
   
 0.842
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair
   
 0.816
WNT1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors
    
 
 0.810
TLE1
Transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
   
 
 0.809
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Pelodiscus sinensis, Trionyx sinensis
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