STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KJE45690.1Penicillin-sensitive transpeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (860 aa)    
Predicted Functional Partners:
KJE46563.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.921
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the SURF1 family.
 
 
0.897
KJE47100.1
Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.891
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.880
KJE46547.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.767
KJE45608.1
D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.
     
 0.753
KJE44712.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.709
KJE46612.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.699
KJE44807.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.699
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
  0.687
Your Current Organism:
Thalassomonas viridans
NCBI taxonomy Id: 137584
Other names: CECT 5083, DSM 13754, T. viridans, Thalassomonas viridans Macian et al. 2001, strain XOM25
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.