node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDJ35445.1 | SDJ95280.1 | SAMN05216186_101231 | SAMN05216186_103322 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase RecQ. | 0.728 |
SDJ35445.1 | SDL14676.1 | SAMN05216186_101231 | SAMN05216186_11597 | ATP-dependent DNA helicase RecQ. | UvrD/REP helicase N-terminal domain-containing protein. | 0.892 |
SDJ35445.1 | SDL60884.1 | SAMN05216186_101231 | SAMN05216186_1254 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.861 |
SDJ35445.1 | SDM03129.1 | SAMN05216186_101231 | SAMN05216186_1429 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase UvrD. | 0.892 |
SDJ35445.1 | recB | SAMN05216186_101231 | SAMN05216186_11223 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombi [...] | 0.661 |
SDJ35445.1 | recD | SAMN05216186_101231 | SAMN05216186_11222 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recomb [...] | 0.845 |
SDJ35445.1 | rep | SAMN05216186_101231 | SAMN05216186_101400 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. | 0.882 |
SDJ35445.1 | sbcD | SAMN05216186_101231 | SAMN05216186_11980 | ATP-dependent DNA helicase RecQ. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.958 |
SDJ95280.1 | SDJ35445.1 | SAMN05216186_103322 | SAMN05216186_101231 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase RecQ. | 0.728 |
SDJ95280.1 | SDL14676.1 | SAMN05216186_103322 | SAMN05216186_11597 | ATP-dependent DNA helicase RecQ. | UvrD/REP helicase N-terminal domain-containing protein. | 0.876 |
SDJ95280.1 | SDL60884.1 | SAMN05216186_103322 | SAMN05216186_1254 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.861 |
SDJ95280.1 | SDM03129.1 | SAMN05216186_103322 | SAMN05216186_1429 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase UvrD. | 0.892 |
SDJ95280.1 | recB | SAMN05216186_103322 | SAMN05216186_11223 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombi [...] | 0.661 |
SDJ95280.1 | recD | SAMN05216186_103322 | SAMN05216186_11222 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recomb [...] | 0.845 |
SDJ95280.1 | rep | SAMN05216186_103322 | SAMN05216186_101400 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. | 0.879 |
SDJ95280.1 | sbcD | SAMN05216186_103322 | SAMN05216186_11980 | ATP-dependent DNA helicase RecQ. | Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.958 |
SDK69694.1 | SDL14676.1 | SAMN05216186_109170 | SAMN05216186_11597 | ATP-dependent DNA helicase RecQ. | UvrD/REP helicase N-terminal domain-containing protein. | 0.876 |
SDK69694.1 | SDL60884.1 | SAMN05216186_109170 | SAMN05216186_1254 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.861 |
SDK69694.1 | SDM03129.1 | SAMN05216186_109170 | SAMN05216186_1429 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase UvrD. | 0.879 |
SDK69694.1 | recB | SAMN05216186_109170 | SAMN05216186_11223 | ATP-dependent DNA helicase RecQ. | DNA helicase/exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombi [...] | 0.661 |