STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdE2_1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (732 aa)    
Predicted Functional Partners:
nrdF2
Ribonucleotide-diphosphate reductase subunit beta; B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
AMC00466.1
Ribonucleoside-diphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
nrdF
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 0.998
AMC00467.1
Ribonucleoside-diphosphate reductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
nrdI_1
Ribonucleotide reduction protein NrdI; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NrdI family.
 
  
 0.973
nrdH_1
NrdH-redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.962
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.929
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.920
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.914
ndk
Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NDK family.
    
 0.914
Your Current Organism:
Aerococcus viridans
NCBI taxonomy Id: 1377
Other names: A. viridans, ATCC 11563, CCUG 4311, CIP 54.145, DSM 20340, Gaffkya homari, IAM 13649, IFO 12219, JCM 20461, LMG 17931, LMG:17931, NBRC 12219, NCAIM B.01070, NCTC 8251, Pediococcus homari
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