node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMC00203.1 | udk | AWM76_00770 | AWM76_04285 | Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
AMC00203.1 | yfkN_1 | AWM76_00770 | AWM76_02975 | Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. | 0.908 |
AMC00878.1 | dnaJ | AWM76_04625 | AWM76_05655 | Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.733 |
AMC00878.1 | udk | AWM76_04625 | AWM76_04285 | Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
cmk | pyrH | AWM76_03875 | AWM76_04640 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.409 |
cmk | udk | AWM76_03875 | AWM76_04285 | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.926 |
dnaJ | AMC00878.1 | AWM76_05655 | AWM76_04625 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Snf2 family helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.733 |
dnaJ | udk | AWM76_05655 | AWM76_04285 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
gap | udk | AWM76_04755 | AWM76_04285 | Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
pyrF | pyrH | AWM76_01410 | AWM76_04640 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.928 |
pyrF | pyrR | AWM76_01410 | AWM76_05130 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Phosphoribosyl transferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.990 |
pyrF | udk | AWM76_01410 | AWM76_04285 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
pyrF | upp | AWM76_01410 | AWM76_05695 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.938 |
pyrH | cmk | AWM76_04640 | AWM76_03875 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
pyrH | pyrF | AWM76_04640 | AWM76_01410 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.928 |
pyrH | pyrR | AWM76_04640 | AWM76_05130 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Phosphoribosyl transferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.923 |
pyrH | udk | AWM76_04640 | AWM76_04285 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.932 |
pyrH | upp | AWM76_04640 | AWM76_05695 | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.955 |
pyrR | pyrF | AWM76_05130 | AWM76_01410 | Phosphoribosyl transferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.990 |
pyrR | pyrH | AWM76_05130 | AWM76_04640 | Phosphoribosyl transferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.923 |