STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBATP-dependent deoxyribonuclease subunit B; ATP-dependent DNA helicase. (1242 aa)    
Predicted Functional Partners:
addA
ATP-dependent nuclease subunit A; ATP-dependent DNA helicase.
 
 0.999
trmK
tRNA-Thr; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.726
pcrA
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.686
ytgP_2
Export protein for polysaccharides and teichoic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.639
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
    
 0.577
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.544
AMC00796.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.528
AMC00866.1
Nif3-like dinuclear metal center hexameric protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.528
sbcD
Exonuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.518
ytgP_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.512
Your Current Organism:
Aerococcus viridans
NCBI taxonomy Id: 1377
Other names: A. viridans, ATCC 11563, CCUG 4311, CIP 54.145, DSM 20340, Gaffkya homari, IAM 13649, IFO 12219, JCM 20461, LMG 17931, LMG:17931, NBRC 12219, NCAIM B.01070, NCTC 8251, Pediococcus homari
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.