STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvH_1Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)    
Predicted Functional Partners:
gcvH_2
Glycine cleavage system protein H; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.982
pdhD_2
Dihydrolipoamide dehydrogenase; E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.955
pdhC
Dihydrolipoamide acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.833
rodA
Rod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family.
  
    0.826
glnA_1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.821
AMC01878.1
Phosphoribosylformylglycinamidine synthase; With PurL and PurS catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.814
gdh
Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
  0.810
pdhB
2-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.787
lipL
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.754
Your Current Organism:
Aerococcus viridans
NCBI taxonomy Id: 1377
Other names: A. viridans, ATCC 11563, CCUG 4311, CIP 54.145, DSM 20340, Gaffkya homari, IAM 13649, IFO 12219, JCM 20461, LMG 17931, LMG:17931, NBRC 12219, NCAIM B.01070, NCTC 8251, Pediococcus homari
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