Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yycF_2PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)    
Predicted Functional Partners:
yycG_1
PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
baeS_1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
phoR
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.945
baeS_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.938
yycG_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.915
arlS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.859
rnjA_2
Metallohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.823
AMC01570.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.814
yycI
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.806
sigA
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.733
Your Current Organism:
Aerococcus viridans
NCBI taxonomy Id: 1377
Other names: A. viridans, ATCC 11563, CCUG 4311, CIP 54.145, DSM 20340, Gaffkya homari, IAM 13649, IFO 12219, JCM 20461, LMG 17931, LMG:17931, NBRC 12219, NCAIM B.01070, NCTC 8251, Pediococcus homari
Server load: medium (42%) [HD]