STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEQ69761.1hydroxymethylglutaryl-CoA synthase. (388 aa)    
Predicted Functional Partners:
SEQ69723.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.999
SEQ53063.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
 0.998
SEQ89327.1
Diphosphomevalonate decarboxylase.
 
 
 0.947
SER25099.1
Formate C-acetyltransferase.
    
  0.935
SEQ89293.1
Mevalonate kinase.
 
 
 0.919
SEQ89377.1
Phosphomevalonate kinase.
 
 
 0.919
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.915
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.909
SEQ60720.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
 
 0.834
SER14540.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
   
 
 0.834
Your Current Organism:
Granulicatella balaenopterae
NCBI taxonomy Id: 137733
Other names: ATCC 700813, Abiotrophia balaenopterae, CCUG 37380, CIP 105938, DSM 15827, G. balaenopterae, strain M1975/96/1
Server load: low (20%) [HD]