STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkAUnannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (365 aa)    
Predicted Functional Partners:
pgi
Unannotated protein; Belongs to the GPI family.
  
 0.979
pyk
Unannotated protein; Belongs to the pyruvate kinase family.
 
 
 0.965
pyk-2
Unannotated protein; Belongs to the pyruvate kinase family.
 
 
 0.965
fba
Unannotated protein.
 
 
 0.910
fbp
Unannotated protein.
     
 0.908
CQ394_16905
Unannotated protein.
 
 
 0.904
pfp
Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
0.904
rpiB
Unannotated protein.
 
 
 0.896
manA
Unannotated protein.
    
 0.889
pfkB
Unannotated protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.888
Your Current Organism:
Clostridium neonatale
NCBI taxonomy Id: 137838
Other names: ATCC BAA-265, C. neonatale, CCUG 46077, strain AIP 250.09, strain LCDC 99A005, strain NML 99-A-005, strain NML 99A005, strain St. Boniface Hospital 30686
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.