STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB64334.1Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. (341 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.508
TopB
KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.508
LolD_4
Putative bacteriocin export ABC transporter; KEGG: scp:HMPREF0833_10128 8.2e-79 ABC transporter ATP-binding protein; Psort location: CytoplasmicMembrane, score: 8.78.
       0.466
KXB64333.1
Efflux ABC transporter, permease protein; KEGG: efu:HMPREF0351_10749 3.0e-38 ABC superfamily ATP binding cassette transporter, membrane protein K02004; Psort location: CytoplasmicMembrane, score: 10.00.
       0.464
KXB63363.1
Cell wall-binding repeat protein; KEGG: smb:smi_1563 7.5e-21 lytC; choline-binding protein LytC, 4-beta-N-acetylmuramidase, Cpb13; Psort location: Extracellular, score: 8.91.
  
  
 0.423
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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