STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB63149.1Hypothetical protein; KEGG: sis:LS215_0050 3.2e-06 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50. (107 aa)    
Predicted Functional Partners:
msrA
Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 0.896
merA
mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.795
KXB62705.1
Dihydrolipoyl dehydrogenase; KEGG: sgo:SGO_1130 6.0e-186 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.
  
 0.766
NrdE
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.740
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.674
KXB59806.1
methionine-R-sulfoxide reductase; KEGG: faa:HMPREF0389_00920 3.8e-49 methionine-S-sulfoxide reductase/methionine-R-sulfoxide reductase; K12267 peptide methionine sulfoxide reductase msrA/msrB; Psort location: Cytoplasmic, score: 7.50.
   
 0.651
Gor
KEGG: yep:YE105_C3776 4.8e-177 glutathione reductase; K00383 glutathione reductase (NADPH); Psort location: Cytoplasmic, score: 9.67.
  
 0.650
Lpd
Pyridine nucleotide-disulfide oxidoreductase; KEGG: snc:HMPREF0837_11823 2.3e-129 lpdG; dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.650
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.627
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.610
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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