STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NrdERibonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (696 aa)    
Predicted Functional Partners:
NrdF
KEGG: ssp:SSP1985 7.4e-117 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526; Psort location: Cytoplasmic, score: 7.50.
 0.999
KXB63160.1
nrdI protein; KEGG: sax:USA300HOU_0754 2.0e-27 nrdI; ribonucleotide reductase stimulatory protein K03647; Belongs to the NrdI family.
 
  
 0.986
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.940
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
 0.920
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.913
Pyk_1
Pyruvate kinase, barrel domain protein; KEGG: clc:Calla_0654 2.8e-64 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
    
 0.902
Pyk_2
Pyruvate kinase; KEGG: afl:Aflv_0500 2.0e-153 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
    
 0.902
Pyk_3
Pyruvate kinase, barrel domain protein; KEGG: chd:Calhy_1460 9.2e-68 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
    
 0.902
RelA_2
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
 0.900
KXB63149.1
Hypothetical protein; KEGG: sis:LS215_0050 3.2e-06 thioredoxin K03671; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.740
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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