| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EfeM | EfeN | HMPREF3186_00201 | HMPREF3186_00200 | Imelysin. | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | 0.996 |
| EfeM | EfeU | HMPREF3186_00201 | HMPREF3186_00199 | Imelysin. | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | 0.993 |
| EfeM | TatAy | HMPREF3186_00201 | HMPREF3186_00197 | Imelysin. | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | 0.813 |
| EfeM | tatC | HMPREF3186_00201 | HMPREF3186_00198 | Imelysin. | Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.814 |
| EfeN | EfeM | HMPREF3186_00200 | HMPREF3186_00201 | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | Imelysin. | 0.996 |
| EfeN | EfeU | HMPREF3186_00200 | HMPREF3186_00199 | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | 0.982 |
| EfeN | TatAy | HMPREF3186_00200 | HMPREF3186_00197 | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | 0.862 |
| EfeN | tatC | HMPREF3186_00200 | HMPREF3186_00198 | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.863 |
| EfeU | EfeM | HMPREF3186_00199 | HMPREF3186_00201 | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | Imelysin. | 0.993 |
| EfeU | EfeN | HMPREF3186_00199 | HMPREF3186_00200 | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | 0.982 |
| EfeU | TatAy | HMPREF3186_00199 | HMPREF3186_00197 | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | 0.838 |
| EfeU | tatC | HMPREF3186_00199 | HMPREF3186_00198 | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.839 |
| HepT | tatC | HMPREF3186_01283 | HMPREF3186_00198 | KEGG: hhd:HBHAL_3282 4.6e-53 hepT; heptaprenyl diphosphate synthase component II K00805; Psort location: Cytoplasmic, score: 9.67; Belongs to the FPP/GGPP synthase family. | Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.491 |
| TatAy | EfeM | HMPREF3186_00197 | HMPREF3186_00201 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Imelysin. | 0.813 |
| TatAy | EfeN | HMPREF3186_00197 | HMPREF3186_00200 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Tat-translocated enzyme; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. | 0.862 |
| TatAy | EfeU | HMPREF3186_00197 | HMPREF3186_00199 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Iron permease FTR1 family protein; KEGG: ccv:CCV52592_0433 3.9e-25 fumarate hydratase class II K01679; Psort location: CytoplasmicMembrane, score: 10.00. | 0.838 |
| TatAy | hemH | HMPREF3186_00197 | HMPREF3186_00079 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.600 |
| TatAy | secD | HMPREF3186_00197 | HMPREF3186_01251 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.665 |
| TatAy | tatC | HMPREF3186_00197 | HMPREF3186_00198 | Twin arginine-targeting protein translocase, TatA/E family; Psort location: CytoplasmicMembrane, score: 9.99. | Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.990 |
| ffh | ftsY | HMPREF3186_01685 | HMPREF3186_00523 | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.993 |