STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (293 aa)    
Predicted Functional Partners:
ThrC
Threonine synthase; KEGG: sri:SELR_19610 3.1e-134 thrC; putative threonine synthase K01733; Psort location: Cytoplasmic, score: 7.50.
 
 0.999
Hom
KEGG: lbh:Lbuc_2305 2.5e-84 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 0.998
purM
KEGG: bmh:BMWSH_4950 9.6e-108 purM; Phosphoribosylformylglycinamidine cyclo-ligase; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97.
    
 0.910
MetH
KEGG: smn:SMA_1241 8.6e-226 5,10-methylenetetrahydrofolate reductase/Homolog of homocysteine-binding domain; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
    
 0.907
ThrA
Amino acid kinase family protein; KEGG: shi:Shel_16060 8.9e-121 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
 
 0.890
MetI
Putative cystathionine beta-lyase; KEGG: bpu:BPUM_1119 4.0e-109 yjcI; cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.874
IlvK
Branched-chain-amino-acid transaminase; KEGG: bmd:BMD_2502 1.6e-112 ilvK; branched-chain amino acid aminotransferase K00826.
  
 
 0.856
SdhB
KEGG: ssd:SPSINT_0934 7.4e-46 L-serine dehydratase subunit beta K01752; Psort location: Cytoplasmic, score: 7.50; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.831
SdhA
KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.831
MetE_2
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.822
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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