STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SpxA_2Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. (119 aa)    
Predicted Functional Partners:
ExoA
Exodeoxyribonuclease III; KEGG: cpr:CPR_1192 4.6e-101 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97.
      0.763
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.543
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.529
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.526
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.515
KXB63080.1
Efflux ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c11620 8.6e-123 putative ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 9.35.
       0.513
MacB_3
KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78.
       0.513
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.439
RpoE
KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.438
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.416
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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