| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ExoA | SpxA_2 | HMPREF3186_00026 | HMPREF3186_00268 | Exodeoxyribonuclease III; KEGG: cpr:CPR_1192 4.6e-101 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97. | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | 0.763 |
| ExoA | rpoZ | HMPREF3186_00026 | HMPREF3186_00426 | Exodeoxyribonuclease III; KEGG: cpr:CPR_1192 4.6e-101 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.441 |
| KXB63080.1 | MacB_3 | HMPREF3186_00266 | HMPREF3186_00267 | Efflux ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c11620 8.6e-123 putative ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 9.35. | KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78. | 0.974 |
| KXB63080.1 | SpxA_2 | HMPREF3186_00266 | HMPREF3186_00268 | Efflux ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c11620 8.6e-123 putative ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 9.35. | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | 0.513 |
| MacB_3 | KXB63080.1 | HMPREF3186_00267 | HMPREF3186_00266 | KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78. | Efflux ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c11620 8.6e-123 putative ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 9.35. | 0.974 |
| MacB_3 | SpxA_2 | HMPREF3186_00267 | HMPREF3186_00268 | KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78. | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | 0.513 |
| MacB_3 | rplS | HMPREF3186_00267 | HMPREF3186_00269 | KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.417 |
| RpoE | SpxA_2 | HMPREF3186_00260 | HMPREF3186_00268 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | 0.438 |
| RpoE | rpoA | HMPREF3186_00260 | HMPREF3186_01796 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.523 |
| RpoE | rpoB | HMPREF3186_00260 | HMPREF3186_01412 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.498 |
| RpoE | rpoC | HMPREF3186_00260 | HMPREF3186_01413 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.575 |
| RpoE | rpoZ | HMPREF3186_00260 | HMPREF3186_00426 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.690 |
| RpoE | sigA | HMPREF3186_00260 | HMPREF3186_00495 | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.584 |
| SpxA_2 | ExoA | HMPREF3186_00268 | HMPREF3186_00026 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | Exodeoxyribonuclease III; KEGG: cpr:CPR_1192 4.6e-101 xth; exodeoxyribonuclease III K01142; Psort location: Cytoplasmic, score: 9.97. | 0.763 |
| SpxA_2 | KXB63080.1 | HMPREF3186_00268 | HMPREF3186_00266 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | Efflux ABC transporter, permease protein; KEGG: sgg:SGGBAA2069_c11620 8.6e-123 putative ABC transporter permease K02004; Psort location: CytoplasmicMembrane, score: 9.35. | 0.513 |
| SpxA_2 | MacB_3 | HMPREF3186_00268 | HMPREF3186_00267 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | KEGG: ssr:SALIVB_1702 4.6e-69 lipoprotein-releasing system ATP-binding protein lolD K02003; Psort location: CytoplasmicMembrane, score: 8.78. | 0.513 |
| SpxA_2 | RpoE | HMPREF3186_00268 | HMPREF3186_00260 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | KEGG: sug:SAPIG2170 5.7e-23 rpoE; DNA-directed RNA polymerase, delta subunit K03048; Psort location: Cytoplasmic, score: 7.50. | 0.438 |
| SpxA_2 | rplS | HMPREF3186_00268 | HMPREF3186_00269 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.515 |
| SpxA_2 | rpoA | HMPREF3186_00268 | HMPREF3186_01796 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.543 |
| SpxA_2 | rpoB | HMPREF3186_00268 | HMPREF3186_01412 | Transcriptional regulator, Spx/MgsR family; KEGG: cpe:CPE2362 7.9e-26 ArsC family protein; K00537 arsenate reductase; Belongs to the ArsC family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.416 |