node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EzrA | KXB62890.1 | HMPREF3186_01753 | HMPREF3186_00355 | Septation ring formation regulator EzrA; KEGG: edi:EDI_341030 2.7e-13 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 9.89. | Hypothetical protein; KEGG: mpu:MYPU_1770 7.8e-21 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.67; Belongs to the UPF0374 family. | 0.572 |
EzrA | nadK | HMPREF3186_01753 | HMPREF3186_00354 | Septation ring formation regulator EzrA; KEGG: edi:EDI_341030 2.7e-13 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 9.89. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.495 |
KXB59674.1 | YqeH | HMPREF3186_01028 | HMPREF3186_01091 | Putative dGTPase; KEGG: bsr:I33_3907 2.3e-90 YwfO K06885; Psort location: Cytoplasmic, score: 7.50. | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | 0.544 |
KXB59674.1 | nadK | HMPREF3186_01028 | HMPREF3186_00354 | Putative dGTPase; KEGG: bsr:I33_3907 2.3e-90 YwfO K06885; Psort location: Cytoplasmic, score: 7.50. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.464 |
KXB62888.1 | KXB62890.1 | HMPREF3186_00353 | HMPREF3186_00355 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein; KEGG: mpu:MYPU_1770 7.8e-21 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.67; Belongs to the UPF0374 family. | 0.774 |
KXB62888.1 | YqeH | HMPREF3186_00353 | HMPREF3186_01091 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | 0.501 |
KXB62888.1 | nadK | HMPREF3186_00353 | HMPREF3186_00354 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.806 |
KXB62888.1 | ribA | HMPREF3186_00353 | HMPREF3186_00294 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.451 |
KXB62890.1 | EzrA | HMPREF3186_00355 | HMPREF3186_01753 | Hypothetical protein; KEGG: mpu:MYPU_1770 7.8e-21 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.67; Belongs to the UPF0374 family. | Septation ring formation regulator EzrA; KEGG: edi:EDI_341030 2.7e-13 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 9.89. | 0.572 |
KXB62890.1 | KXB62888.1 | HMPREF3186_00355 | HMPREF3186_00353 | Hypothetical protein; KEGG: mpu:MYPU_1770 7.8e-21 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.67; Belongs to the UPF0374 family. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.774 |
KXB62890.1 | nadK | HMPREF3186_00355 | HMPREF3186_00354 | Hypothetical protein; KEGG: mpu:MYPU_1770 7.8e-21 cysS; cysteinyl-tRNA synthetase (cysteine--tRNA ligase) K01883; Psort location: Cytoplasmic, score: 9.67; Belongs to the UPF0374 family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.804 |
KXB63106.1 | nadD | HMPREF3186_00292 | HMPREF3186_01093 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.711 |
KXB63106.1 | nadE | HMPREF3186_00292 | HMPREF3186_01569 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.579 |
KXB63106.1 | nadK | HMPREF3186_00292 | HMPREF3186_00354 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.433 |
KXB63106.1 | ribA | HMPREF3186_00292 | HMPREF3186_00294 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
TlyA | nadK | HMPREF3186_01429 | HMPREF3186_00354 | Ribosomal RNA large subunit methyltransferase J; KEGG: lin:lin1403 1.6e-80 hypothetical protein; K06442 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase; Psort location: Cytoplasmic, score: 7.50. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.508 |
YqeH | KXB59674.1 | HMPREF3186_01091 | HMPREF3186_01028 | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | Putative dGTPase; KEGG: bsr:I33_3907 2.3e-90 YwfO K06885; Psort location: Cytoplasmic, score: 7.50. | 0.544 |
YqeH | KXB62888.1 | HMPREF3186_01091 | HMPREF3186_00353 | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.501 |
YqeH | nadD | HMPREF3186_01091 | HMPREF3186_01093 | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.869 |
YqeH | nadK | HMPREF3186_01091 | HMPREF3186_00354 | Ribosome biogenesis GTPase YqeH; KEGG: bcy:Bcer98_3061 2.9e-106 GTP-binding protein YqeH K06948; Psort location: Cytoplasmic, score: 7.50. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.483 |