STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB62449.1KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. (708 aa)    
Predicted Functional Partners:
PbpX
KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51.
 
 
 0.881
KXB61962.1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
 
 
 0.762
RodA
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 1.5e-29 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
 
 
 0.743
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
   
 0.739
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
  
 0.701
GpsB
Putative cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
 
 
 0.660
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.615
mltG
YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
 
   
 0.606
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
   
 0.594
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
   
 0.577
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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