STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TrxA_3Thioredoxin; KEGG: bqy:MUS_3122 3.8e-26 trxA; deoxyribodipyrimidine photo-lyase K03671; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family. (101 aa)    
Predicted Functional Partners:
TrxA_1
Thioredoxin; KEGG: ant:Arnit_1790 8.2e-15 thioredoxin; K03672 thioredoxin 2; Belongs to the thioredoxin family.
  
     0.772
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.767
GroS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.
  
 
 0.694
TrxB_2
KEGG: bcy:Bcer98_3701 3.4e-105 thioredoxin reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.67.
  
 
 0.591
KXB62705.1
Dihydrolipoyl dehydrogenase; KEGG: sgo:SGO_1130 6.0e-186 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.579
TrxB_1
Putative thioredoxin-disulfide reductase; KEGG: cdc:CD196_2197 1.0e-94 trxB3; thioredoxin reductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 9.97.
  
 
 0.569
YfkJ
Putative low molecular weight protein-tyrosine-phosphatase PtpA; KEGG: lba:Lebu_2236 4.2e-59 protein tyrosine phosphatase; K01104 protein-tyrosine phosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.491
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
   
 
 0.458
KXB59107.1
Redoxin family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.449
Gap
Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.446
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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