STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GlnRPutative HTH-type transcriptional regulator GlnR; KEGG: rpm:RSPPHO_00344 3.2e-06 MerR family transcriptional regulator; Psort location: Cytoplasmic, score: 9.67. (127 aa)    
Predicted Functional Partners:
GlnA
KEGG: bst:GYO_2106 2.7e-183 glnA; glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.942
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.677
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.561
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.541
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.531
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.507
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.483
KXB62235.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.477
KXB62129.1
KEGG: bcl:ABC0052 2.2e-29 holB; DNA polymerase III subunit delta' K02341; Psort location: Cytoplasmic, score: 7.50.
 
 
   0.431
KXB62237.1
Pseudouridylate synthase; KEGG: tte:TTE0052 1.9e-63 RsuA; 16S rRNA uridine-516 pseudouridylate synthase; K06183 16S rRNA pseudouridine516 synthase; Psort location: Cytoplasmic, score: 9.97.
       0.429
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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