STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BrnQ_1Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids. (444 aa)    
Predicted Functional Partners:
KXB62244.1
Hypothetical protein; KEGG: snc:HMPREF0837_11960 2.3e-09 ABC transporter ATP-binding protein K01990.
       0.475
KXB62245.1
Hypothetical protein; KEGG: zin:ZICARI_096 0.0018 nuoN; putative NADH:ubiquinone oxidoreductase I, membrane subunit N; K00343 NADH-quinone oxidoreductase subunit N; Psort location: CytoplasmicMembrane, score: 10.00.
       0.475
YoaE
Integral membrane protein, YkoY family; KEGG: cco:CCC13826_1787 3.2e-13 S-adenosylmethionine synthetase (methionineadenosyltransferase; AdoMet synthetase; MAT); Psort location: CytoplasmicMembrane, score: 10.00.
       0.461
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.419
KXB57270.1
Methionine synthase, vitamin-B12 independent; KEGG: scp:HMPREF0833_10873 5.0e-127 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.418
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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