STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DnaIPrimosomal protein DnaI family protein; KEGG: rcm:A1E_01215 4.6e-06 fmt; methionyl-tRNA formyltransferase K06916; Psort location: Cytoplasmic, score: 7.50; Belongs to the DnaA family. (294 aa)    
Predicted Functional Partners:
DnaB
Replication initiation and membrane attachment protein, DnaB/DnaD family; KEGG: sax:USA300HOU_1672 7.4e-30 dnaB2; replicative DNA helicase K03346; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.949
KXB62216.1
Hypothetical protein; KEGG: sum:SMCARI_281 0.00013 hypothetical protein; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50.
     
 0.776
DnaC
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.678
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.587
KXB62225.1
POTRA domain protein, FtsQ-type; Essential cell division protein.
 
     0.571
DnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
  
 0.570
KXB60265.1
Phage/plasmid primase, P4 family domain protein; KEGG: llm:llmg_2252 5.0e-69 ps517; putative DNA primase K06919.
  
 
 0.567
KXB63643.1
KEGG: ser:SERP1154 7.3e-55 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50.
 
   
 0.566
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
   
 
 0.508
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
       0.467
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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