| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB57901.1 | PgsA_1 | HMPREF3186_01546 | HMPREF3186_00467 | Ser/Thr phosphatase family protein; KEGG: bce:BC1111 3.9e-47 phosphoesterase K07098; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.544 |
| KXB62145.1 | PgsA_1 | HMPREF3186_00466 | HMPREF3186_00467 | Hypothetical protein; KEGG: ssr:SALIVB_2089 3.0e-26 tyrosyl-tRNA synthetase; Psort location: CytoplasmicMembrane, score: 9.55. | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.511 |
| PgsA_1 | KXB57901.1 | HMPREF3186_00467 | HMPREF3186_01546 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Ser/Thr phosphatase family protein; KEGG: bce:BC1111 3.9e-47 phosphoesterase K07098; Psort location: CytoplasmicMembrane, score: 10.00. | 0.544 |
| PgsA_1 | KXB62145.1 | HMPREF3186_00467 | HMPREF3186_00466 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Hypothetical protein; KEGG: ssr:SALIVB_2089 3.0e-26 tyrosyl-tRNA synthetase; Psort location: CytoplasmicMembrane, score: 9.55. | 0.511 |
| PgsA_1 | PgsA_2 | HMPREF3186_00467 | HMPREF3186_01695 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: sut:SAT0131_01339 1.5e-56 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.944 |
| PgsA_1 | Psd | HMPREF3186_00467 | HMPREF3186_01089 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.984 |
| PgsA_1 | SdhA | HMPREF3186_00467 | HMPREF3186_00099 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| PgsA_1 | SdhB | HMPREF3186_00467 | HMPREF3186_00098 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: ssd:SPSINT_0934 7.4e-46 L-serine dehydratase subunit beta K01752; Psort location: Cytoplasmic, score: 7.50; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.900 |
| PgsA_1 | glyA | HMPREF3186_00467 | HMPREF3186_00536 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| PgsA_1 | metAA | HMPREF3186_00467 | HMPREF3186_00196 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.800 |
| PgsA_1 | trpB | HMPREF3186_00467 | HMPREF3186_01565 | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| PgsA_2 | PgsA_1 | HMPREF3186_01695 | HMPREF3186_00467 | KEGG: sut:SAT0131_01339 1.5e-56 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.944 |
| PgsA_2 | Psd | HMPREF3186_01695 | HMPREF3186_01089 | KEGG: sut:SAT0131_01339 1.5e-56 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.654 |
| Psd | PgsA_1 | HMPREF3186_01089 | HMPREF3186_00467 | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.984 |
| Psd | PgsA_2 | HMPREF3186_01089 | HMPREF3186_01695 | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | KEGG: sut:SAT0131_01339 1.5e-56 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.654 |
| SdhA | PgsA_1 | HMPREF3186_00099 | HMPREF3186_00467 | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| SdhA | SdhB | HMPREF3186_00099 | HMPREF3186_00098 | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: ssd:SPSINT_0934 7.4e-46 L-serine dehydratase subunit beta K01752; Psort location: Cytoplasmic, score: 7.50; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.999 |
| SdhA | glyA | HMPREF3186_00099 | HMPREF3186_00536 | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.946 |
| SdhA | metAA | HMPREF3186_00099 | HMPREF3186_00196 | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.803 |
| SdhA | trpB | HMPREF3186_00099 | HMPREF3186_01565 | KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |