STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IlvKBranched-chain-amino-acid transaminase; KEGG: bmd:BMD_2502 1.6e-112 ilvK; branched-chain amino acid aminotransferase K00826. (361 aa)    
Predicted Functional Partners:
MetI
Putative cystathionine beta-lyase; KEGG: bpu:BPUM_1119 4.0e-109 yjcI; cystathionine gamma-synthase K01739; Psort location: Cytoplasmic, score: 9.97.
  
 0.926
gshAB
Glutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
  
 
 0.914
Hom
KEGG: lbh:Lbuc_2305 2.5e-84 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.902
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.856
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.849
PflB
KEGG: gmc:GY4MC1_3791 2.3e-271 formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
    
  0.800
MetH
KEGG: smn:SMA_1241 8.6e-226 5,10-methylenetetrahydrofolate reductase/Homolog of homocysteine-binding domain; K00547 homocysteine S-methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.594
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.545
PatA
Putative aromatic-amino-acid transaminase; KEGG: stb:SGPB_0023 7.5e-92 patA; aminotransferase K00841; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.524
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
  
 0.516
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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