Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KXB61968.1Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (453 aa)    
Predicted Functional Partners:
XanP
Putative permease; KEGG: apb:SAR116_1372 1.5e-40 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.928
PunA
Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.921
Hpt
KEGG: sgo:SGO_2134 4.8e-58 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.912
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.904
deoD
KEGG: mcl:MCCL_0129 2.1e-80 purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.67.
    
  0.900
KXB57734.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
KXB61969.1
Hypothetical protein.
       0.564
luxS
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
    0.480
YgfU
Xanthine permease; KEGG: apb:SAR116_1372 3.4e-64 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
  
 0.437
KXB59055.1
Hypothetical protein; KEGG: cth:Cthe_1169 8.4e-16 beta-lactamase class A-like protein; K01467 beta-lactamase.
  
    0.414
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.