node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB61975.1 | murB | HMPREF3186_00541 | HMPREF3186_00542 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.929 |
PbpX | ddl | HMPREF3186_00447 | HMPREF3186_01722 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.793 |
PbpX | mraY | HMPREF3186_00447 | HMPREF3186_00448 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.971 |
PbpX | murA | HMPREF3186_00447 | HMPREF3186_00390 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.826 |
PbpX | murB | HMPREF3186_00447 | HMPREF3186_00542 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.787 |
PbpX | murC | HMPREF3186_00447 | HMPREF3186_01055 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.915 |
PbpX | murD | HMPREF3186_00447 | HMPREF3186_00449 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.976 |
PbpX | murE | HMPREF3186_00447 | HMPREF3186_01245 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.879 |
PbpX | murF | HMPREF3186_00447 | HMPREF3186_01723 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.909 |
PbpX | murG | HMPREF3186_00447 | HMPREF3186_00908 | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.700 |
ddl | PbpX | HMPREF3186_01722 | HMPREF3186_00447 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.793 |
ddl | mraY | HMPREF3186_01722 | HMPREF3186_00448 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.736 |
ddl | murA | HMPREF3186_01722 | HMPREF3186_00390 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.553 |
ddl | murB | HMPREF3186_01722 | HMPREF3186_00542 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.973 |
ddl | murC | HMPREF3186_01722 | HMPREF3186_01055 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.986 |
ddl | murD | HMPREF3186_01722 | HMPREF3186_00449 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.852 |
ddl | murE | HMPREF3186_01722 | HMPREF3186_01245 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.704 |
ddl | murF | HMPREF3186_01722 | HMPREF3186_01723 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ddl | murG | HMPREF3186_01722 | HMPREF3186_00908 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.768 |
mraY | PbpX | HMPREF3186_00448 | HMPREF3186_00447 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.971 |