Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (260 aa)    
Predicted Functional Partners:
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 0.999
ThiD
Phosphomethylpyrimidine kinase; KEGG: std:SPPN_03705 3.5e-87 bifunctional hydroxy-methylpyrimidine kinase/hydroxy-phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 7.50.
  
 0.997
TenA
TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
  
 0.996
NudF
Hydrolase, NUDIX family; KEGG: eat:EAT1b_0457 7.8e-42 NUDIX hydrolase; K01515 ADP-ribose pyrophosphatase; Psort location: Cytoplasmic, score: 7.50.
    
  0.900
KXB61452.1
Hypothetical protein; KEGG: ccs:CCNA_03554 6.0e-20 esterase Lipase family protein; Psort location: Cytoplasmic, score: 7.50.
       0.456
KXB58355.1
KEGG: ooe:OEOE_0791 1.6e-27 thiamine pyrophosphokinase; K00949 thiamine pyrophosphokinase; Psort location: Cytoplasmic, score: 7.50.
     
 0.424
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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