STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DltAKEGG: dsy:DSY0221 1.4e-106 D-alanine--poly(phosphoribitol) ligase subunit 1 K03367; Psort location: Cytoplasmic, score: 9.67; Belongs to the ATP-dependent AMP-binding enzyme family. (500 aa)    
Predicted Functional Partners:
dltC
D-alanine--poly(phosphoribitol) ligase, subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 0.998
DltB
Putative protein DltB; KEGG: bya:BANAU_3754 2.0e-75 dltB; putative poly(beta-D-mannuronate) O-acetylase K03739; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the membrane-bound acyltransferase family.
  
 0.995
DltD
DltD protein; KEGG: pfa:PF13_0120 2.5e-05 conserved Plasmodium protein, unknown function.
 
  
 0.993
ddl
D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
  
 
 0.916
mef
H+ Antiporter protein; KEGG: bqy:MUS_1487 6.8e-24 ykuC; MFS transporter, DHA3 family, macrolide efflux protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.807
acpP
Putative acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.803
KXB59790.1
KEGG: sha:SH1920 2.7e-27 hypothetical protein; K02552 menaquinone-specific isochorismate synthase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.611
ActIII
KEGG: btk:BT9727_3881 6.9e-50 oxidoreductase, short-chain dehydrogenase/reductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.530
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
    
 0.506
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
    0.475
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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