STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB61138.1KEGG: shn:Shewana3_3590 4.7e-12 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.67. (150 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.827
TopB
KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.827
KXB61139.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.727
KXB61140.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.727
KXB61141.1
Hypothetical protein; KEGG: ngr:NAEGRDRAFT_78079 0.0059 serine/threonine-protein kinase; K04728 ataxia telangiectasia mutated family protein; Psort location: Cytoplasmic, score: 7.50.
       0.727
KXB61142.1
Hypothetical protein; KEGG: fjo:Fjoh_3354 0.0015 multi-sensor hybrid histidine kinase K00936.
       0.727
DnaE
KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95.
 
 
 
 0.623
KXB61133.1
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
   
 
 0.619
rplJ
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
    0.615
priA
Primosomal protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
 
 
 0.610
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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