STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CcpNPutative transcriptional repressor CcpN; KEGG: ppo:PPM_2177 2.3e-35 yqzB; inosine-5'-monophosphate dehydrogenase IMP dehydrogenase; IMPDH; IMPD; Psort location: Cytoplasmic, score: 7.50. (212 aa)    
Predicted Functional Partners:
YqfL
Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.938
PpdK
Pyruvate, phosphate dikinase; KEGG: cdf:CD2410 1.8e-289 ppdK; pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
 
    0.763
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.651
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.521
KXB60327.1
DRTGG domain protein; KEGG: bya:BANAU_2851 4.8e-90 ytoI; Inosine-5'-monophosphate dehydrogenase IMP dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
     0.493
KXB60297.1
Hypothetical protein; KEGG: edi:EDI_031160 3.3e-06 cingulin.
       0.470
KXB60296.1
LPXTG-motif protein cell wall anchor domain protein; Psort location: Cellwall, score: 9.24.
       0.449
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
   
 0.431
KXB57951.1
KEGG: bmd:BMD_0076 7.5e-37 tetrapyrrole methylase family protein / MazG family protein K02499; Psort location: Cytoplasmic, score: 7.50.
 
     0.417
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.