STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB60192.1Hypothetical protein; KEGG: stj:SALIVA_1198 1.8e-67 dinB2; DNA polymerase IV 2 (Pol IV 2); Psort location: CytoplasmicMembrane, score: 9.55. (190 aa)    
Predicted Functional Partners:
UmuC
Hypothetical protein; KEGG: ssr:SALIVB_0903 3.3e-66 dinB2; DNA polymerase IV 2 (Pol IV 2) K03502; Psort location: Cytoplasmic, score: 7.50.
     0.994
KXB60277.1
Hypothetical protein; KEGG: stj:SALIVA_1198 2.3e-21 dinB2; DNA polymerase IV 2 (Pol IV 2).
 
     0.976
KXB60194.1
Peptidase S24-like protein; KEGG: sgg:SGGBAA2069_c10720 5.6e-48 transcriptional regulator.
 
     0.845
DnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.724
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.682
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.597
KXB57613.1
Putative repressor LexA; KEGG: asm:MOUSESFB_0090 5.5e-25 XRE family transcriptional regulator; K01356 repressor LexA; Psort location: Cytoplasmic, score: 7.50; Belongs to the peptidase S24 family.
  
 
 0.581
KXB60195.1
Hypothetical protein; KEGG: mps:MPTP_1048 7.4e-13 beta-lactamase.
       0.522
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.486
TopB
KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.486
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.