| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BcrC | KXB60197.1 | HMPREF3186_00884 | HMPREF3186_00885 | PAP2 family protein; KEGG: scp:HMPREF0833_11020 4.0e-22 lipid phosphate phosphohydrolase 2 family protein; Psort location: CytoplasmicMembrane, score: 10.00. | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.767 |
| BcrC | mraY | HMPREF3186_00884 | HMPREF3186_00448 | PAP2 family protein; KEGG: scp:HMPREF0833_11020 4.0e-22 lipid phosphate phosphohydrolase 2 family protein; Psort location: CytoplasmicMembrane, score: 10.00. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.911 |
| KXB60197.1 | BcrC | HMPREF3186_00885 | HMPREF3186_00884 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | PAP2 family protein; KEGG: scp:HMPREF0833_11020 4.0e-22 lipid phosphate phosphohydrolase 2 family protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.767 |
| KXB60197.1 | KXB61962.1 | HMPREF3186_00885 | HMPREF3186_00528 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.519 |
| KXB60197.1 | KXB62225.1 | HMPREF3186_00885 | HMPREF3186_00450 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.648 |
| KXB60197.1 | PbpX | HMPREF3186_00885 | HMPREF3186_00447 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.559 |
| KXB60197.1 | ftsZ | HMPREF3186_00885 | HMPREF3186_00783 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.665 |
| KXB60197.1 | mraY | HMPREF3186_00885 | HMPREF3186_00448 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.545 |
| KXB60197.1 | murC | HMPREF3186_00885 | HMPREF3186_01055 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.619 |
| KXB60197.1 | murD | HMPREF3186_00885 | HMPREF3186_00449 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.651 |
| KXB60197.1 | murE | HMPREF3186_00885 | HMPREF3186_01245 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.541 |
| KXB60197.1 | murF | HMPREF3186_00885 | HMPREF3186_01723 | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.609 |
| KXB61962.1 | KXB60197.1 | HMPREF3186_00528 | HMPREF3186_00885 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Monogalactosyldiacylglycerol synthase protein; KEGG: slg:SLGD_01851 8.5e-84 diglucosyldiacylglycerol synthase; K03429 1,2-diacylglycerol 3-glucosyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.519 |
| KXB61962.1 | KXB62225.1 | HMPREF3186_00528 | HMPREF3186_00450 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.761 |
| KXB61962.1 | PbpX | HMPREF3186_00528 | HMPREF3186_00447 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.959 |
| KXB61962.1 | ftsZ | HMPREF3186_00528 | HMPREF3186_00783 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.587 |
| KXB61962.1 | mraY | HMPREF3186_00528 | HMPREF3186_00448 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.881 |
| KXB61962.1 | murC | HMPREF3186_00528 | HMPREF3186_01055 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.883 |
| KXB61962.1 | murD | HMPREF3186_00528 | HMPREF3186_00449 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.879 |
| KXB61962.1 | murE | HMPREF3186_00528 | HMPREF3186_01245 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.647 |