| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FemX | KXB57598.1 | HMPREF3186_01548 | HMPREF3186_01651 | FemAB family protein; KEGG: ssr:SALIVB_1141 5.9e-60 femX; aminoacyltransferase femX K05363; Psort location: Cytoplasmic, score: 9.97. | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.925 |
| FemX | KXB57599.1 | HMPREF3186_01548 | HMPREF3186_01652 | FemAB family protein; KEGG: ssr:SALIVB_1141 5.9e-60 femX; aminoacyltransferase femX K05363; Psort location: Cytoplasmic, score: 9.97. | CobB/CobQ-like protein; KEGG: sax:USA300HOU_1889 2.0e-75 adenosylcobyric acid synthase (glutamine-hydrolyzing) K07009. | 0.912 |
| FemX | murG | HMPREF3186_01548 | HMPREF3186_00908 | FemAB family protein; KEGG: ssr:SALIVB_1141 5.9e-60 femX; aminoacyltransferase femX K05363; Psort location: Cytoplasmic, score: 9.97. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.921 |
| KXB57598.1 | FemX | HMPREF3186_01651 | HMPREF3186_01548 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | FemAB family protein; KEGG: ssr:SALIVB_1141 5.9e-60 femX; aminoacyltransferase femX K05363; Psort location: Cytoplasmic, score: 9.97. | 0.925 |
| KXB57598.1 | KXB57599.1 | HMPREF3186_01651 | HMPREF3186_01652 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | CobB/CobQ-like protein; KEGG: sax:USA300HOU_1889 2.0e-75 adenosylcobyric acid synthase (glutamine-hydrolyzing) K07009. | 0.999 |
| KXB57598.1 | mraY | HMPREF3186_01651 | HMPREF3186_00448 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.549 |
| KXB57598.1 | murC | HMPREF3186_01651 | HMPREF3186_01055 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.525 |
| KXB57598.1 | murD | HMPREF3186_01651 | HMPREF3186_00449 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.559 |
| KXB57598.1 | murF | HMPREF3186_01651 | HMPREF3186_01723 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.614 |
| KXB57598.1 | murG | HMPREF3186_01651 | HMPREF3186_00908 | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.949 |
| KXB57599.1 | FemX | HMPREF3186_01652 | HMPREF3186_01548 | CobB/CobQ-like protein; KEGG: sax:USA300HOU_1889 2.0e-75 adenosylcobyric acid synthase (glutamine-hydrolyzing) K07009. | FemAB family protein; KEGG: ssr:SALIVB_1141 5.9e-60 femX; aminoacyltransferase femX K05363; Psort location: Cytoplasmic, score: 9.97. | 0.912 |
| KXB57599.1 | KXB57598.1 | HMPREF3186_01652 | HMPREF3186_01651 | CobB/CobQ-like protein; KEGG: sax:USA300HOU_1889 2.0e-75 adenosylcobyric acid synthase (glutamine-hydrolyzing) K07009. | Mur ligase middle domain protein; KEGG: sab:SAB1824c 1.9e-111 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| KXB57599.1 | murG | HMPREF3186_01652 | HMPREF3186_00908 | CobB/CobQ-like protein; KEGG: sax:USA300HOU_1889 2.0e-75 adenosylcobyric acid synthase (glutamine-hydrolyzing) K07009. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.901 |
| KXB61962.1 | mraY | HMPREF3186_00528 | HMPREF3186_00448 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.881 |
| KXB61962.1 | murB | HMPREF3186_00528 | HMPREF3186_00542 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.521 |
| KXB61962.1 | murC | HMPREF3186_00528 | HMPREF3186_01055 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.883 |
| KXB61962.1 | murD | HMPREF3186_00528 | HMPREF3186_00449 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.879 |
| KXB61962.1 | murF | HMPREF3186_00528 | HMPREF3186_01723 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.845 |
| KXB61962.1 | murG | HMPREF3186_00528 | HMPREF3186_00908 | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 5.4e-43 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.858 |
| coaD | murG | HMPREF3186_00907 | HMPREF3186_00908 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.813 |