| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ActIII | CopY | HMPREF3186_01100 | HMPREF3186_01099 | KEGG: btk:BT9727_3881 6.9e-50 oxidoreductase, short-chain dehydrogenase/reductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 2.8e-14 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | 0.732 |
| ActIII | KXB59596.1 | HMPREF3186_01100 | HMPREF3186_01101 | KEGG: btk:BT9727_3881 6.9e-50 oxidoreductase, short-chain dehydrogenase/reductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.546 |
| CopY | ActIII | HMPREF3186_01099 | HMPREF3186_01100 | Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 2.8e-14 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | KEGG: btk:BT9727_3881 6.9e-50 oxidoreductase, short-chain dehydrogenase/reductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.732 |
| CopY | KXB59596.1 | HMPREF3186_01099 | HMPREF3186_01101 | Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 2.8e-14 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.432 |
| KXB59570.1 | KXB59596.1 | HMPREF3186_01075 | HMPREF3186_01101 | LPXTG-motif protein cell wall anchor domain protein; KEGG: sds:SDEG_0714 1.9e-130 extracellular nuclease K07004; Psort location: Cellwall, score: 9.98. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.900 |
| KXB59596.1 | ActIII | HMPREF3186_01101 | HMPREF3186_01100 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | KEGG: btk:BT9727_3881 6.9e-50 oxidoreductase, short-chain dehydrogenase/reductase K07124; Psort location: Cytoplasmic, score: 9.97; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.546 |
| KXB59596.1 | CopY | HMPREF3186_01101 | HMPREF3186_01099 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | Copper transport repressor, CopY/TcrY family; KEGG: bcz:BCZK0993 2.8e-14 blaI; beta-lactamase K07737; Psort location: Cytoplasmic, score: 7.50. | 0.432 |
| KXB59596.1 | KXB59570.1 | HMPREF3186_01101 | HMPREF3186_01075 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | LPXTG-motif protein cell wall anchor domain protein; KEGG: sds:SDEG_0714 1.9e-130 extracellular nuclease K07004; Psort location: Cellwall, score: 9.98. | 0.900 |
| KXB59596.1 | PunA | HMPREF3186_01101 | HMPREF3186_01592 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.531 |
| KXB59596.1 | deoD | HMPREF3186_01101 | HMPREF3186_01268 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | KEGG: mcl:MCCL_0129 2.1e-80 purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.67. | 0.525 |
| KXB59596.1 | guaB | HMPREF3186_01101 | HMPREF3186_00296 | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.683 |
| PunA | KXB59596.1 | HMPREF3186_01592 | HMPREF3186_01101 | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.531 |
| PunA | deoD | HMPREF3186_01592 | HMPREF3186_01268 | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | KEGG: mcl:MCCL_0129 2.1e-80 purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.67. | 0.951 |
| PunA | guaB | HMPREF3186_01592 | HMPREF3186_00296 | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.582 |
| deoD | KXB59596.1 | HMPREF3186_01268 | HMPREF3186_01101 | KEGG: mcl:MCCL_0129 2.1e-80 purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.67. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.525 |
| deoD | PunA | HMPREF3186_01268 | HMPREF3186_01592 | KEGG: mcl:MCCL_0129 2.1e-80 purine nucleoside phosphorylase; K03784 purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score: 9.67. | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.951 |
| guaB | KXB59596.1 | HMPREF3186_00296 | HMPREF3186_01101 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | LPXTG-motif protein cell wall anchor domain protein; KEGG: ssa:SSA_1234 8.1e-219 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: Cellwall, score: 10.00; Belongs to the 5'-nucleotidase family. | 0.683 |
| guaB | PunA | HMPREF3186_00296 | HMPREF3186_01592 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Inosine guanosine and xanthosine phosphorylase family protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.582 |