STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB59539.12-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: sca:Sca_0932 9.3e-142 putative pyruvate flavodoxin/ferredoxin oxidoreductase; K00174 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Psort location: Cytoplasmic, score: 7.50. (588 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.999
PorB
2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family; KEGG: bco:Bcell_2424 3.3e-91 pyruvate ferredoxin/flavodoxin oxidoreductase subunit beta K00175; Psort location: Cytoplasmic, score: 7.50.
 0.999
TopB
KEGG: cbn:CbC4_2099 9.8e-186 DNA topoisomerase III; K03169 DNA topoisomerase III; Psort location: Cytoplasmic, score: 9.97.
  
   0.999
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.980
Pta
Phosphate acetyltransferase; KEGG: ssp:SSP2124 1.9e-104 eutD; phosphotransacetylase; K00625 phosphate acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
    
 0.963
PpdK
Pyruvate, phosphate dikinase; KEGG: cdf:CD2410 1.8e-289 ppdK; pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
    
 0.962
AldA
Putative succinate-semialdehyde dehydrogenase; KEGG: nmq:NMBM04240196_1906 4.9e-168 aldA; aldehyde dehydrogenase A K07248; Psort location: Cytoplasmic, score: 9.97.
  
 0.958
KXB62705.1
Dihydrolipoyl dehydrogenase; KEGG: sgo:SGO_1130 6.0e-186 dihydrolipoamide dehydrogenase K00382; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.957
PflB
KEGG: gmc:GY4MC1_3791 2.3e-271 formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
    
 0.949
Pyk_1
Pyruvate kinase, barrel domain protein; KEGG: clc:Calla_0654 2.8e-64 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
  
 0.947
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.