node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB60301.1 | PbpX | HMPREF3186_00798 | HMPREF3186_00447 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.891 |
KXB60301.1 | RodA | HMPREF3186_00798 | HMPREF3186_01106 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 1.5e-29 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.763 |
KXB60301.1 | mraY | HMPREF3186_00798 | HMPREF3186_00448 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.603 |
KXB60301.1 | murA | HMPREF3186_00798 | HMPREF3186_00390 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.584 |
KXB60301.1 | murC | HMPREF3186_00798 | HMPREF3186_01055 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.751 |
KXB60301.1 | murD | HMPREF3186_00798 | HMPREF3186_00449 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.591 |
KXB60301.1 | murF | HMPREF3186_00798 | HMPREF3186_01723 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.609 |
KXB60301.1 | murG | HMPREF3186_00798 | HMPREF3186_00908 | Transglycosylase; KEGG: sha:SH1462 5.9e-140 pbp2; penicillin-binding protein 2; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.515 |
KXB62225.1 | PbpX | HMPREF3186_00450 | HMPREF3186_00447 | POTRA domain protein, FtsQ-type; Essential cell division protein. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.978 |
KXB62225.1 | RodA | HMPREF3186_00450 | HMPREF3186_01106 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 1.5e-29 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.726 |
KXB62225.1 | mraY | HMPREF3186_00450 | HMPREF3186_00448 | POTRA domain protein, FtsQ-type; Essential cell division protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.879 |
KXB62225.1 | murC | HMPREF3186_00450 | HMPREF3186_01055 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.806 |
KXB62225.1 | murD | HMPREF3186_00450 | HMPREF3186_00449 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.960 |
KXB62225.1 | murF | HMPREF3186_00450 | HMPREF3186_01723 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.686 |
KXB62225.1 | murG | HMPREF3186_00450 | HMPREF3186_00908 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.676 |
KXB62449.1 | PbpX | HMPREF3186_00394 | HMPREF3186_00447 | KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51. | 0.881 |
KXB62449.1 | RodA | HMPREF3186_00394 | HMPREF3186_01106 | KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: hiq:CGSHiGG_09345 1.5e-29 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase K03588; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. | 0.743 |
KXB62449.1 | mraY | HMPREF3186_00394 | HMPREF3186_00448 | KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.615 |
KXB62449.1 | murA | HMPREF3186_00394 | HMPREF3186_00390 | KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.577 |
KXB62449.1 | murC | HMPREF3186_00394 | HMPREF3186_01055 | KEGG: gka:GK2168 4.8e-129 penicillin-binding protein 1A/1B; K05366 penicillin-binding protein 1A; Psort location: CytoplasmicMembrane, score: 9.51. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.739 |