STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshABGlutamate--cysteine ligase/gamma-glutamylcysteine synthetase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine; In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily. (753 aa)    
Predicted Functional Partners:
IlvK
Branched-chain-amino-acid transaminase; KEGG: bmd:BMD_2502 1.6e-112 ilvK; branched-chain amino acid aminotransferase K00826.
  
 
 0.914
pepA
Putative leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.904
GlnA
KEGG: bst:GYO_2106 2.7e-183 glnA; glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.885
CysK
KEGG: vpr:Vpar_0141 5.8e-101 cysteine synthase; K01738 cysteine synthase A; Psort location: Cytoplasmic, score: 7.50.
    
 0.876
KXB60321.1
Glutamate dehydrogenase, NAD-specific; KEGG: cba:CLB_1746 8.0e-136 gluD; glutamate dehydrogenase K00260; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.812
PatB
Aminotransferase, class I/II; KEGG: fnu:FN0625 2.2e-110 aspartate aminotransferase K14155; Psort location: Cytoplasmic, score: 7.50.
    
  0.800
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.682
PbpX
KEGG: mcl:MCCL_0753 1.1e-154 pbpA; penicillin-binding protein 1; K12552 penicillin-binding protein 1; Psort location: CytoplasmicMembrane, score: 9.51.
  
 
 0.632
KXB59383.1
FAH family protein; KEGG: sax:USA300HOU_0927 4.9e-81 fumarylacetoacetase; Psort location: Cytoplasmic, score: 7.50.
  
    0.619
KXB62225.1
POTRA domain protein, FtsQ-type; Essential cell division protein.
  
  
 0.609
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.