| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fba | Gap | HMPREF3186_01717 | HMPREF3186_00283 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 0.977 |
| Fba | Rpe | HMPREF3186_01717 | HMPREF3186_01432 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | 0.412 |
| Fba | Tkt | HMPREF3186_01717 | HMPREF3186_01169 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | Transketolase; KEGG: ssa:SSA_2075 2.4e-260 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family. | 0.958 |
| Fba | eno | HMPREF3186_01717 | HMPREF3186_00280 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.963 |
| Fba | guaB | HMPREF3186_01717 | HMPREF3186_00296 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.454 |
| Fba | pfkA | HMPREF3186_01717 | HMPREF3186_01364 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.944 |
| Fba | pgi | HMPREF3186_01717 | HMPREF3186_00801 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | KEGG: lmf:LMOf2365_2338 8.0e-175 pgi; glucose-6-phosphate isomerase; K01810 glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.944 |
| Fba | tal | HMPREF3186_01717 | HMPREF3186_00841 | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.955 |
| Gap | Fba | HMPREF3186_00283 | HMPREF3186_01717 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | 0.977 |
| Gap | Tkt | HMPREF3186_00283 | HMPREF3186_01169 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Transketolase; KEGG: ssa:SSA_2075 2.4e-260 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family. | 0.932 |
| Gap | eno | HMPREF3186_00283 | HMPREF3186_00280 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.970 |
| Gap | guaB | HMPREF3186_00283 | HMPREF3186_00296 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.561 |
| Gap | pfkA | HMPREF3186_00283 | HMPREF3186_01364 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.777 |
| Gap | pgi | HMPREF3186_00283 | HMPREF3186_00801 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | KEGG: lmf:LMOf2365_2338 8.0e-175 pgi; glucose-6-phosphate isomerase; K01810 glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family. | 0.941 |
| Gap | tal | HMPREF3186_00283 | HMPREF3186_00841 | Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: efa:EF1964 7.0e-144 gap-2; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97. | Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.901 |
| Rpe | Fba | HMPREF3186_01432 | HMPREF3186_01717 | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50. | 0.412 |
| Rpe | Tkt | HMPREF3186_01432 | HMPREF3186_01169 | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | Transketolase; KEGG: ssa:SSA_2075 2.4e-260 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family. | 0.991 |
| Rpe | eno | HMPREF3186_01432 | HMPREF3186_00280 | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.479 |
| Rpe | guaB | HMPREF3186_01432 | HMPREF3186_00296 | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.527 |
| Rpe | prs | HMPREF3186_01432 | HMPREF3186_00537 | KEGG: esi:Exig_1921 7.4e-62 ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 7.50. | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.508 |