| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DnaE | DnaN | HMPREF3186_01363 | HMPREF3186_00018 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.990 |
| DnaE | KXB59371.1 | HMPREF3186_01363 | HMPREF3186_01189 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97. | 0.699 |
| DnaE | KXB62129.1 | HMPREF3186_01363 | HMPREF3186_00487 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | KEGG: bcl:ABC0052 2.2e-29 holB; DNA polymerase III subunit delta' K02341; Psort location: Cytoplasmic, score: 7.50. | 0.755 |
| DnaE | KXB63643.1 | HMPREF3186_01363 | HMPREF3186_00121 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | KEGG: ser:SERP1154 7.3e-55 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50. | 0.989 |
| DnaE | dnaX | HMPREF3186_01363 | HMPREF3186_01166 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.770 |
| DnaE | metG | HMPREF3186_01363 | HMPREF3186_01264 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.587 |
| DnaE | polA | HMPREF3186_01363 | HMPREF3186_00816 | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.740 |
| DnaN | DnaE | HMPREF3186_00018 | HMPREF3186_01363 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | 0.990 |
| DnaN | KXB59371.1 | HMPREF3186_00018 | HMPREF3186_01189 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97. | 0.729 |
| DnaN | KXB62129.1 | HMPREF3186_00018 | HMPREF3186_00487 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bcl:ABC0052 2.2e-29 holB; DNA polymerase III subunit delta' K02341; Psort location: Cytoplasmic, score: 7.50. | 0.686 |
| DnaN | KXB63643.1 | HMPREF3186_00018 | HMPREF3186_00121 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ser:SERP1154 7.3e-55 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50. | 0.992 |
| DnaN | dnaX | HMPREF3186_00018 | HMPREF3186_01166 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.800 |
| DnaN | metG | HMPREF3186_00018 | HMPREF3186_01264 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.428 |
| DnaN | polA | HMPREF3186_00018 | HMPREF3186_00816 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
| KXB59370.1 | KXB59371.1 | HMPREF3186_01188 | HMPREF3186_01189 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: lsi:HN6_00620 2.4e-70 CCA-adding enzyme (tRNA nucleotidyltransferase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA CCA-pyrophosphorylase) (tRNA-NT); Psort location: Cytoplasmic, score: 7.50. | Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97. | 0.762 |
| KXB59370.1 | asnS | HMPREF3186_01188 | HMPREF3186_01190 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: lsi:HN6_00620 2.4e-70 CCA-adding enzyme (tRNA nucleotidyltransferase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA CCA-pyrophosphorylase) (tRNA-NT); Psort location: Cytoplasmic, score: 7.50. | asparagine--tRNA ligase; KEGG: bha:BH1696 6.1e-161 asnC; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 10.00. | 0.626 |
| KXB59370.1 | metG | HMPREF3186_01188 | HMPREF3186_01264 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: lsi:HN6_00620 2.4e-70 CCA-adding enzyme (tRNA nucleotidyltransferase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA CCA-pyrophosphorylase) (tRNA-NT); Psort location: Cytoplasmic, score: 7.50. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.578 |
| KXB59370.1 | nth | HMPREF3186_01188 | HMPREF3186_01192 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: lsi:HN6_00620 2.4e-70 CCA-adding enzyme (tRNA nucleotidyltransferase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA CCA-pyrophosphorylase) (tRNA-NT); Psort location: Cytoplasmic, score: 7.50. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.504 |
| KXB59370.1 | polA | HMPREF3186_01188 | HMPREF3186_00816 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: lsi:HN6_00620 2.4e-70 CCA-adding enzyme (tRNA nucleotidyltransferase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA CCA-pyrophosphorylase) (tRNA-NT); Psort location: Cytoplasmic, score: 7.50. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.440 |
| KXB59371.1 | DnaE | HMPREF3186_01189 | HMPREF3186_01363 | Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97. | KEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. | 0.699 |