STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DnaEKEGG: bmq:BMQ_4779 3.9e-175 dnaE; DNA polymerase III subunit alpha K02337; Psort location: Cytoplasmic, score: 9.95. (1085 aa)    
Predicted Functional Partners:
DnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.990
KXB63643.1
KEGG: ser:SERP1154 7.3e-55 holA; DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50.
  
 0.989
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
0.933
dnaX
DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.770
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.769
KXB62129.1
KEGG: bcl:ABC0052 2.2e-29 holB; DNA polymerase III subunit delta' K02341; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.755
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
 
 0.740
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
     0.707
KXB59371.1
Interleukin-1 / 18; KEGG: lsn:LSA_07000 7.4e-26 hypothetical protein; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.699
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
   
 0.669
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.