STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pgi
KEGG: lmf:LMOf2365_2338 8.0e-175 pgi; glucose-6-phosphate isomerase; K01810 glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 0.978
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.950
Fba
Fructose-1,6-bisphosphate aldolase, class II; KEGG: csh:Closa_0465 1.9e-111 fructose-1,6-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.944
Tkt
Transketolase; KEGG: ssa:SSA_2075 2.4e-260 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family.
  
 
 0.935
YdjH
Kinase, PfkB family; KEGG: cdf:CD1806 9.0e-57 scrK; fructokinase; K00847 fructokinase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.932
tal
Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.931
LacC
1-phosphofructokinase; KEGG: aur:HMPREF9243_1310 1.4e-69 pfkB; 1-phosphofructokinase K00882; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.927
fbp
KEGG: lmh:LMHCC_1800 9.9e-193 fbp; fructose-1,6-bisphosphatase; K04041 fructose-1,6-bisphosphatase III; Psort location: Cytoplasmic, score: 7.50.
     
 0.919
GmuF
KEGG: bag:Bcoa_0535 4.2e-82 mannose-6-phosphate isomerase; K01809 mannose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 7.50.
    
 0.914
Pyk_2
Pyruvate kinase; KEGG: afl:Aflv_0500 2.0e-153 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.816
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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