STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pyk_3Pyruvate kinase, barrel domain protein; KEGG: chd:Calhy_1460 9.2e-68 pyruvate kinase; K00873 pyruvate kinase; Psort location: Cytoplasmic, score: 7.50. (382 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.962
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.959
KXB59539.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: sca:Sca_0932 9.3e-142 putative pyruvate flavodoxin/ferredoxin oxidoreductase; K00174 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Psort location: Cytoplasmic, score: 7.50.
  
 0.947
KXB59653.1
Putative D-lactate dehydrogenase; KEGG: mcl:MCCL_0071 9.5e-85 D-specific D-2-hydroxyacid dehydrogenase; K03778 D-lactate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.934
AldA
Putative succinate-semialdehyde dehydrogenase; KEGG: nmq:NMBM04240196_1906 4.9e-168 aldA; aldehyde dehydrogenase A K07248; Psort location: Cytoplasmic, score: 9.97.
  
 0.927
PorB
2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family; KEGG: bco:Bcell_2424 3.3e-91 pyruvate ferredoxin/flavodoxin oxidoreductase subunit beta K00175; Psort location: Cytoplasmic, score: 7.50.
  
 0.924
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.917
pgi
KEGG: lmf:LMOf2365_2338 8.0e-175 pgi; glucose-6-phosphate isomerase; K01810 glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 
 0.916
PdhB
KEGG: ssq:SSUD9_1865 4.0e-109 pdhB; pyruvate dehydrogenase E1 component subunit beta; K00162 pyruvate dehydrogenase E1 component subunit beta; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.914
AcoA
Putative TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit; KEGG: lba:Lebu_0541 8.6e-107 pyruvate dehydrogenase; K00161 pyruvate dehydrogenase E1 component subunit alpha; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.914
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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