STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (402 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.927
SdhB
KEGG: ssd:SPSINT_0934 7.4e-46 L-serine dehydratase subunit beta K01752; Psort location: Cytoplasmic, score: 7.50; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
SdhA
KEGG: ssd:SPSINT_0935 2.8e-92 L-serine dehydratase subunit alpha K01752; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.900
PgsA_1
KEGG: cbe:Cbei_0572 4.4e-32 CDP-diacylglycerol--serine O-phosphatidyltransferase; K00998 phosphatidylserine synthase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.900
GloA
KEGG: efu:HMPREF0351_12081 6.4e-47 gloA3; lactoylglutathione lyase K01759; Psort location: Cytoplasmic, score: 7.50.
  
  0.838
AldA
Putative succinate-semialdehyde dehydrogenase; KEGG: nmq:NMBM04240196_1906 4.9e-168 aldA; aldehyde dehydrogenase A K07248; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.837
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
    
  0.834
HchA
Protein in dcm-seru intergenic region; KEGG: reh:H16_B1347 1.4e-74 chaperone protein HchA K05523; Psort location: Cytoplasmic, score: 9.67.
    
  0.819
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.697
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.565
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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