STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB57613.1Putative repressor LexA; KEGG: asm:MOUSESFB_0090 5.5e-25 XRE family transcriptional regulator; K01356 repressor LexA; Psort location: Cytoplasmic, score: 7.50; Belongs to the peptidase S24 family. (210 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.945
dinB
Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
 
 0.681
RecN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.656
KXB60192.1
Hypothetical protein; KEGG: stj:SALIVA_1198 1.8e-67 dinB2; DNA polymerase IV 2 (Pol IV 2); Psort location: CytoplasmicMembrane, score: 9.55.
  
 
 0.581
UmuC
Hypothetical protein; KEGG: ssr:SALIVB_0903 3.3e-66 dinB2; DNA polymerase IV 2 (Pol IV 2) K03502; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.581
KXB57614.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.536
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.531
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.456
cinA
Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 4.5e-15 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: CytoplasmicMembrane, score: 8.16; Belongs to the CinA family.
     
 0.449
RecJ
single-stranded-DNA-specific exonuclease RecJ; KEGG: sha:SH1285 1.8e-131 hypothetical protein; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 7.50.
     
 0.445
Your Current Organism:
Gemella haemolysans
NCBI taxonomy Id: 1379
Other names: ATCC 10379, CCUG 37985, CIP 101126, G. haemolysans, LMG 18984, LMG:18984, NCTC 12968, Neisseria haemolysans
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