node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXB57623.1 | KXB57631.1 | HMPREF3186_01676 | HMPREF3186_01684 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.787 |
KXB57623.1 | TrmK | HMPREF3186_01676 | HMPREF3186_00832 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: lsl:LSL_0846 2.8e-53 hypothetical protein; K06967 tRNA (adenine22-N1)-methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.632 |
KXB57623.1 | polC | HMPREF3186_01676 | HMPREF3186_00391 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.621 |
KXB57623.1 | whiA | HMPREF3186_01676 | HMPREF3186_01258 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Involved in cell division and chromosome segregation. | 0.650 |
KXB57631.1 | KXB57623.1 | HMPREF3186_01684 | HMPREF3186_01676 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.787 |
KXB57631.1 | KXB57633.1 | HMPREF3186_01684 | HMPREF3186_01686 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | 0.757 |
KXB57631.1 | KXB57636.1 | HMPREF3186_01684 | HMPREF3186_01689 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.557 |
KXB57631.1 | RsmB | HMPREF3186_01684 | HMPREF3186_01196 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.597 |
KXB57631.1 | TrmK | HMPREF3186_01684 | HMPREF3186_00832 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | KEGG: lsl:LSL_0846 2.8e-53 hypothetical protein; K06967 tRNA (adenine22-N1)-methyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.681 |
KXB57631.1 | era | HMPREF3186_01684 | HMPREF3186_01688 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.557 |
KXB57631.1 | ffh | HMPREF3186_01684 | HMPREF3186_01685 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.934 |
KXB57631.1 | polC | HMPREF3186_01684 | HMPREF3186_00391 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.570 |
KXB57631.1 | whiA | HMPREF3186_01684 | HMPREF3186_01258 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Hypothetical protein; Involved in cell division and chromosome segregation. | 0.677 |
KXB57631.1 | ybeY | HMPREF3186_01684 | HMPREF3186_01687 | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.557 |
KXB57633.1 | KXB57631.1 | HMPREF3186_01686 | HMPREF3186_01684 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Helix-turn-helix protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. | 0.757 |
KXB57633.1 | KXB57636.1 | HMPREF3186_01686 | HMPREF3186_01689 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.569 |
KXB57633.1 | RsmB | HMPREF3186_01686 | HMPREF3186_01196 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.473 |
KXB57633.1 | era | HMPREF3186_01686 | HMPREF3186_01688 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.566 |
KXB57633.1 | ffh | HMPREF3186_01686 | HMPREF3186_01685 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.773 |
KXB57633.1 | ybeY | HMPREF3186_01686 | HMPREF3186_01687 | RNA methyltransferase, TrmH family, group 2; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.635 |